Degraded attentional modulation of cortical neural populations in strabismic amblyopia

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چکیده

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Degraded attentional modulation of cortical neural populations in strabismic amblyopia

Behavioral studies have reported reduced spatial attention in amblyopia, a developmental disorder of spatial vision. However, the neural populations in the visual cortex linked with these behavioral spatial attention deficits have not been identified. Here, we use functional MRI-informed electroencephalography source imaging to measure the effect of attention on neural population activity in th...

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Strabismic amblyopia.

NOTWITHSTANDING the vast literature, a complete and satisfactory definition of the clinical picture of amblyopia in strabismus has not yet been produced, and some symptoms are often confused with those of other forms of functional amblyopia. Bangerter (1953) and many other authors embrace in the term " amblyopia ex anopsia" the amblyopia observed in anisometropia, in high ametropia, and in nyst...

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The neural deficit in strabismic amblyopia: sampling considerations

In order to understand the nature of the neural loss in strabismic amblyopia, we have applied a technique which has been used in the normal periphery to psychophysically probe the sampling properties of the neuronal population. We ask whether there is a 'sampling' deficit and if so whether it is based on either an absolute loss of neurons (i.e. spatial undersampling) or an irregular arrangement...

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Image segregation in strabismic amblyopia

Humans with naturally occurring amblyopia show deficits thought to involve mechanisms downstream of V1. These include excessive crowding, abnormal global image processing, spatial sampling and symmetry detection and undercounting. Several recent studies suggest that humans with naturally occurring amblyopia show deficits in global image segregation. The current experiments were designed to stud...

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Integration of local orientation in strabismic amblyopia

In order to investigate the processes which integrate local orientation information in observers with strabismic amblyopia, we measured contrast thresholds for discriminating the global orientation of a pattern (3 "bars") comprised of Gabor patches. We found that in both eyes of amblyopic observers, as has been reported for normal observers [Saarinen, Levi & Shen (1997) Proceedings of the Natio...

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ژورنال

عنوان ژورنال: Journal of Vision

سال: 2016

ISSN: 1534-7362

DOI: 10.1167/16.3.16